Abstract Search

ea0041gp237 | Thyroid Cancer (1) | ECE2016

The origin of patients with inherited medullary thyroid cancer, who are carriers of the rare exon 8 mutation (G533C) of the RET gene in Greece

Saltiki Katerina , Anagnostou Elli , Angelopoulou Anastasia , Kouki Sofia , Apostolakis Michail , Sarika Lida , Papathoma Alexandra , Alevizaki Maria

Introduction: Mutations in the ret gene are responsible for the transmission of inherited medullary thyroid cancer (MTC). In recent years a high prevalence of the rare exon 8 mutation (G533C) has been found in patients with inherited MTC in Greece. The aim of this study was to record with more detail the place of origin of these families in the country.Design: We analysed the details of 44 patients belonging to 22 families who were c...

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ea0035p1102 | Thyroid Cancer | ECE2014

Familial medullary thyroid carcinomas: RET mutation in exon 8 is associated with better prognosis but increased risk for other malignancies

Saltiki Katerina , Rentziou Gianna , Angelopoulou Anastasia , Apostolakis Michael , Papathoma Alexandra , Alevizaki Maria

Objectives: In familial MTC there is genotype-phenotype correlation. The phenotype and clinical outcome in exon8 (G533C) carriers has not been well established.Methods: 95 patients operated for familial MTC (27.2% males) were followed for 0.930 years (mean 8.0, median 5.5 years). 45.3% (n=43) were exon8 carriers (exon8MTC) and the remaning were non-exon8MTCs (n=52, exons 10, 11, 13, 14, and 16). Pre-, postoperative calcitonin, ext...

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ea0093oc43 | Oral communication 7: Diabetes, Obesity and Metabolism | EYES2023

Statin use and perimenopausal BMI determine the risk of incident diabetes mellitus in the postmenopause: Results of Palladia study

Mavraganis George , Papanikola Nektaria , Angelopoulou Anastasia , Stefanaki Aikaterini , Armeni Eleni , Paschou Stavroula , Anelli Valentina , Augoulea Areti , Stamatelopoulos Kimon , Lambrinoudaki Irene

Background: The menopausal transition has been associated with a heightened risk of cardiometabolic complications, including new onset diabetes mellitus (NODM). Statin-use increases the NODM-risk in the general population, however, their impact on NODM-risk specifically in postmenopausal populations has not been adequately studied.Objectives: To estimate the effect of statin-use at baseline on the risk of NODM in postmenopausal women.<p class="abstex...

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Endocrine Abstracts

The origin of patients with inherited medullary thyroid cancer, who are carriers of the rare exon 8 mutation (G533C) of the RET gene in Greece

Familial medullary thyroid carcinomas: RET mutation in exon 8 is associated with better prognosis but increased risk for other malignancies

Statin use and perimenopausal BMI determine the risk of incident diabetes mellitus in the postmenopause: Results of Palladia study

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